2K Sports a annoncé les titres qui composeront la bande son de NBA 2K10.

Au programme, des artistes d'envergure internationale pour une tracklist plutôt diversifiée :

- Ace Hood – Top of the World
- Adam Tensta – My Cool
- Akala – The Edge
- Al Kapone – Rock This
- Chali2na – Lock it Down (Instrumental)
- Chali2na – International (feat. Beenie Man)
- Donnie Bravo – Run Away
- Duo Live - Shootin
- Flo Rida - ROOTS
- Iglu & Hartly – In this City
- Illinois – Hang On
- Izza Kizza – They’re Everywhere
- K’naan – Wavin’ the Flag
- Kanye West – Amazing
- Kenan Bell – Like This
- Matisyahu – One Day
- Metric – Help I’m Alive
- Metronomy – Radio Ladio
- MGMT – Electric Feel
- Miike Snow – Black & Blue
- Naïve New Breeders – Can’t Choose
- Ratatat – Falcon Jab
- Ratatat – Mirando
- Saul Williams – List of Demands (Reparations)
- Sportsrushaz – Iron
- The Game – Champion (Exclusive and original track)
- The Moog – Joyclad Armies
- Vincent Van Go Go – Do You Know